Race-ethnic disparities in the impact of stroke risk factors - The Northern Manhattan Stroke Study
Race-ethnic disparities in the impact of stroke risk factors - The Northern Manhattan Stroke Study
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DOI：
10.1161/01.str.32.8.1725
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发表时间：
2001-08-01
期刊：
影响因子：
8.3
通讯作者：
Shea, S
中科院分区：
文献类型：
--
作者：
Sacco, RL;Boden-Albala, B;Shea, S
背景和目的-卒中危险因素在很大程度上是通过对白色人群的流行病学研究确定的;因此，卒中发病率和死亡率的种族-民族差异仍然无法解释。在本研究的目的是比较的患病率，OR，和病因分数（EF）的中风危险因素之间的白色，黑人，和加勒比海西班牙裔生活在同一个城市社区的北方曼哈顿. Methods，在这个以人口为基础的事件病例对照研究，首次缺血性中风的情况下（n=688）进行前瞻性匹配1：2的年龄，性别和种族，种族与社区对照（n=1156）。通过亲自评估确定风险因素。使用条件logistic回归计算每个种族-种族组的校正OR。患病率和多变量EF在每个种族ethnic group.Results-Hypertension是一个独立的危险因素，白人（OR 1.8，EF 25%），黑人（OR 2.0，EF 37%），和加勒比西班牙裔（OR 2.1，EF 32%），但更大的患病率导致EF升高黑人和加勒比西班牙裔。糖尿病患病率增加了黑人（OR 1.8，EF 14%）和加勒比海西班牙裔（OR 2.1，P
Background and Purpose-Stroke risk factors have been determined in large part through epidemiological studies in white cohorts; as a result, race-ethnic disparities in stroke incidence and mortality rates remained unexplained. The aim in the present study was to compare the prevalence, OR, and etiological fraction (EF) of stroke risk factors among white, blacks, and Caribbean Hispanics living in the same urban community of northern Manhattan.Methods-In this population-based incident case-control study, cases (n=688) of first ischemic stroke were prospectively matched 1:2 by age, sex, and race-ethnicity with community controls (n=1156). Risk factors were determined through in-person assessment. Conditional logistic regression was used to calculate adjusted ORs in each race-ethnic group. Prevalence and multivariate EFs were determined in each race-ethnic group.Results-Hypertension was an independent risk factor for whites (OR 1.8, EF 25%), blacks (OR 2.0, EF 37%), and Caribbean Hispanics (OR 2.1, EF 32%), but greater prevalence led to elevated EFs among blacks and Caribbean Hispanics. Greater prevalence rates of diabetes increased stroke risk in blacks (OR 1.8, EF 14%) and Caribbean Hispanics (OR 2.1 P