Application value of MRI combined with positron emission tomography (PET)/CT in diagnosis and preoperative staging of tongue squamous cell carcinoma
Application value of MRI combined with positron emission tomography (PET)/CT in diagnosis and preoperative staging of tongue squamous cell carcinoma
复制标题
MRI联合正电子发射断层扫描(PET)/CT在舌鳞状细胞癌诊断及术前分期中的应用价值
DOI：
10.1111/1754-9485.12282
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发表时间：
2015-04-01
影响因子：
1.6
通讯作者：
Liang, Changhong
中科院分区：
文献类型：
--
作者：
Chen, Wenbo;Zhang, Chunxing;Liang, Changhong
引言本研究旨在比较分析舌鳞状细胞癌（TSCC）的MRI和正电子发射断层扫描（PET）/CT的表现，探讨MRI-PET/CT联合技术在舌鳞状细胞癌（TSCC）诊断和术前分期中的诊断价值。方法对18例舌鳞状细胞癌（TSCC）的MRI和PET/CT数据进行前瞻性分析。术前根据美国癌症联合委员会（AJCC）分期标准对病例进行MRI和PET/CT综合分期，并经病理结果证实。结果单纯MRI、单纯PET/CT和联合MRI-PET/CT术前AJCC分期I-IV期的最高和最低敏感度分别为100.0%、100.0%和100.0%（II期）和50.4%，分别为 55.6% 和 55.6%（第一阶段）。最高特异性分别为100.0%、100.0%和100.0%（II期），最高正确率分别为100.0%、96.5%和100.0%（II期）。术前I～II期、IV期分期与术后病理分期比较，差异无统计学意义（P>0.05）； Ⅲ期有显着性差异(P<0.05)，但IV期有显着性差异(P0.05)。
IntroductionThis study aimed to compare and analyse the findings of tongue squamous cell carcinoma (TSCC) on MRI and positron emission tomography (PET)/CT and explore the diagnostic utility of combined MRI-PET/CT in the diagnosis and preoperative staging of TSCC.MethodsA prospective analysis of MRI and PET/CT data in 18 TSCC cases was performed. Cases were comprehensively staged on MRI and PET/CT preoperatively according to American Joint Committee on Cancer (AJCC) staging criteria and confirmed by pathological results.ResultsThe highest and lowest sensitivities of preoperative AJCC staging I-IV using MRI alone, PET/CT alone and combined MRI-PET/CT were 100.0%, 100.0% and 100.0% (stage II) and 50.4%, 55.6% and 55.6% (stage I), respectively. The highest specificities were 100.0%, 100.0% and 100.0% (stage II), and the highest correct rates were 100.0%, 96.5% and 100.0% (stage II). Compared with the postoperative pathological staging, preoperative staging showed no significant difference for stages I-II and IV (P>0.05); however, stage III showed a significant difference (P0.05), but there was a significant difference for stage IV (P