Effect of citric acid clearance on the saturation with respect to hydroxyapatite in saliva.
Effect of citric acid clearance on the saturation with respect to hydroxyapatite in saliva.
复制标题
柠檬酸清除率对唾液中羟基磷灰石饱和度的影响。
DOI：
10.1159/000262162
复制
发表时间：
1996
期刊：
影响因子：
4.2
通讯作者：
F. Lagerlöf
中科院分区：
文献类型：
--
作者：
E. Bashir;F. Lagerlöf
饮料和食物中含有的柠檬酸是导致牙釉质侵蚀的主要原因之一。据推测，唾液中柠檬酸的清除会影响唾液相对于羟基磷灰石(OHAp)的饱和度。10名受试者用2%柠檬酸，pH 2.1，漂洗5s。分别在冲洗前、冲洗后1、2、5、10、15分钟采集唾液样本。测定了样品的pH值、离子强度以及离子钙、无机磷和柠檬酸的浓度。唾液pH值从零时的7.21+或-0.40(平均值+或-SD)降至漂洗后1min的最低值6.46+或-0.88。15min后恢复至基线值。在零点唾液相对于OHAp是过饱和的。在用柠檬酸冲洗后，除一个个体外，所有个体的饱和水平都转变为不饱和。在漂洗后的1分钟和2分钟，唾液平均不饱和。5min后，平均饱和度恢复到过饱和水平。个体差异很大。柠檬酸清除率与OHAp在漂洗后1、2、5min的最小饱和度呈显著正相关(r值分别为0.84、0.76和0.79)。总而言之，用柠檬酸漂洗会导致OHAp的饱和度水平下降，这是一种高度个性化的模式。
Citric acid contained in beverages and foods is one of the main causes of enamel erosion. It was hypothesized that the clearance of citric acid from saliva would influence the degree of salivary saturation with respect to hydroxyapatite (OHAp). Ten subjects rinsed with 2% citric acid, pH 2.1, for 5s. Before and at 1,2, 5, 10 and 15 min after the rinse, a small saliva sample was collected. The sample pH, ionic strength and the concentrations of ionized calcium, inorganic phosphate and citric acid were determined. The pH of the saliva decreased from 7.21 + or - 0.40 (mean + or - SD) at time zero to a minimum of 6.46 + or - 0.88 at 1 min after the rinse. It was back to baseline value after 15 min. The saliva was supersaturated with respect to OHAp at time zero. After the rinse with the citric acid the saturation level shifted to undersaturation in all individuals except one. At 1 and 2 min after the rinse the saliva was, on average, undersaturated. After 5 min the average saturation level was back to supersaturation. The individual differences were large. The correlations between the rate of clearance of citric acid during the 1 minute and the minimum degree of saturation with respect to OHAp at 1,2 and 5 min after the rinse were significant (r 0.84, r 0.76 and r 0.79, respectively). In conclusion, rinsing with citric acid will cause a decrease in the saturation level with respect to OHAp in a highly individual pattern.