A Robust 3D Finite Element Simulation of Human Proximal Femur Progressive Fracture Under Stance Load with Experimental Validation
A Robust 3D Finite Element Simulation of Human Proximal Femur Progressive Fracture Under Stance Load with Experimental Validation
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DOI：
10.1007/s10439-013-0864-9
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发表时间：
2013-12-01
影响因子：
3.8
通讯作者：
Allaoui, Samir
中科院分区：
文献类型：
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作者：
Hambli, Ridha;Allaoui, Samir
股骨近端（髋关节）骨折的基于定量计算机断层扫描的有限元分析（QCT/FEA）的临床实施需要（i）开发能够描述髋关节完全失效前渐进性骨折过程的骨材料行为。和（ii）验证模型与现实的测试数据，代表典型的髋部骨折。本研究的目的是开发和实验验证一个准确的三维有限元（FE）模型耦合到一个准脆性损伤法，以模拟人类股骨近端骨折考虑的启动和渐进扩展的多个裂纹阶段下的准静态负载。该模型是基于连续损伤力学，可以预测髋部骨折更充分的物理条件比基于标准的断裂模型。为了验证该模型，10人股骨近端进行了测试，直到完全骨折下单腿站立准静态载荷。生成QCT/FE模型，并在这些股骨上进行FE模拟，施加的载荷和边界条件与站立实验相同。建议的有限元模型导致良好的协议（R（2）= 0.9432）之间的预测和测量结果有关的力-位移曲线（屈服和断裂）的形状和断裂边缘的轮廓。这项工作的动机是提出一个有限元模型，可能的临床使用与模拟的复杂性和能力之间的良好的妥协。
Clinical implementation of quantitative computed tomography-based finite element analysis (QCT/FEA) of proximal femur (hip) fractures requires (i) to develop a bone material behavior able to describe the progressive fracturing process until complete failure of the hip. And (ii) to validate the model with realistic test data that represent typical hip fractures. The objective of the current study was to develop and experimentally validate an accurate 3D finite element (FE) model coupled to a quasi-brittle damage law to simulate human proximal femur fracture considering the initiation and progressive propagation of multiple cracks phases under quasi-static load. The model is based on continuum damage mechanics that can predict hip fracture in more adequate physical terms than criteria-based fracture models. In order to validate the model, ten human proximal femurs were tested until complete fracture under one-legged stance quasi-static load. QCT/FE models were generated and FE simulations were performed on these femurs with the same applied loads and boundary conditions than in the stance experiments. The proposed FE model leads to excellent agreement (R (2) = 0.9432) between predicted and measured results concerning the shape of the force-displacement curve (yielding and fracturing) and the profile of the fractured edge. The motivation of this work was to propose a FE model for possible clinical use with a good compromise between complexity and capability of the simulation.