A diffusion tensor imaging study on the auditory system and tinnitus.
A diffusion tensor imaging study on the auditory system and tinnitus.
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DOI：
10.2174/1874440001004010016
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发表时间：
2010-06-30
期刊：
影响因子：
--
通讯作者：
Roerdink, Jos B T M
中科院分区：
文献类型：
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作者：
Crippa, Alessandro;Lanting, Cris P;Roerdink, Jos B T M
耳鸣是在没有外部声源的情况下的听觉感受。耳鸣的病因有哪些？耳鸣的病因有哪些？扩散张量成像（DTI）是一种磁共振成像技术，允许在体内探索人类大脑中的白色物质组织。使用概率DTI方法，我们确定了从下丘到内侧膝状体到初级听觉皮层的纤维束的特征。我们还研究了听觉系统和杏仁核之间的联系，这可能与某些形式的耳鸣有关。白色物质束由三个量表征：平均分数各向异性、加权平均分数各向异性和路径强度。所有这些量都是白色物质束开放性的量度。最重要的发现是与健康对照组相比，耳鸣患者听觉皮层和杏仁核之间的白色物质束的开放性增加。
Tinnitus is an auditory percept in the absence of an external sound source. Mechanisms in the central nervous system are believed to be key in the pathophysiology of tinnitus. Diffusion tensor imaging (DTI) is an MR imaging technique that allows in vivo exploration of white matter tissue in the human brain. Using a probabilistic DTI approach, we determined the characteristics of fiber tracts from the inferior colliculus to the medial geniculate body up to the primary auditory cortex. We also investigated the connections between the auditory system and the amygdala, which may be involved in some forms of tinnitus. White matter tracts were characterized by three quantities: the mean fractional anisotropy, the weighted mean fractional anisotropy and the path strength. All these quantities are measures of the patency of white matter tracts. The most important finding is an increased patency of the white matter tracts between the auditory cortex and the amygdala in tinnitus patients as compared to healthy controls.