Effect of Maternal Heart Disease on Fetal Growth
Effect of Maternal Heart Disease on Fetal Growth
复制标题
DOI：
10.1097/aog.0b013e31820cab69
复制
发表时间：
2011-04-01
影响因子：
7.2
通讯作者：
Johnson, Mark
中科院分区：
文献类型：
--
作者：
Gelson, Emily;Curry, Ruth;Johnson, Mark
目的：评估孕产妇心脏病对胎儿生长和新生儿结局的影响。方法：对 1994 年至 2010 年间入住切尔西和威斯敏斯特医院的所有患有先天性和后天性心脏病的女性进行回顾性队列研究。将每次妊娠前和妊娠后立即分娩的妇女用作对照。数据来自医疗和产科记录。使用定制的出生体重百分位数程序计算出生体重百分位数，并记录新生儿并发症（早产、围产期死亡率和先天性心脏病复发）。 结果：与对照组（n = 49）相比，心脏病组（n = 31）的中位出生体重百分位数显着较低；P
OBJECTIVE: To estimate the effect of maternal heart disease on fetal growth and neonatal outcomes.METHODS: A retrospective cohort study of all women with congenital and acquired heart disease admitted at Chelsea and Westminster Hospital between 1994 and 2010 was performed. The women who delivered immediately before and immediately after each index pregnancy were used as controls. Data were obtained from medical and obstetric notes. Birth weight percentiles were calculated using a customized birth weight percentile program, and neonatal complications (preterm birth, perinatal mortality, and recurrence of congenital heart disease) were noted.RESULTS: Median birth weight percentile was significantly lower in the heart disease group (n=31) compared with the control group (n=49; P