Ensuring respiratory phase consistency to improve cardiac function quantification in real-time CMR.

Ensuring respiratory phase consistency to improve cardiac function quantification in real-time CMR.
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DOI:
10.1002/mrm.29064
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发表时间:
2022-03
影响因子:
3.3
通讯作者:
Ahmad R
Ahmad R
中科院分区:
医学3区
文献类型:
--
作者:
Chen C;Chandrasekaran P;Liu Y;Simonetti OP;Tong M;Ahmad R

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开发一种自动选择具有一致呼吸相位的心跳的方法,以提高实时(RT)心脏 MRI 中心脏功能量化的准确性。通过主成分分析方法从 RT 电影图像中提取呼吸信号。然后,使用两步程序来确定呼吸信号的方向性(符号)。以手动选择的感兴趣区域中的运动作为参考,使用来自 11 名志愿者和 10 名患者的多切片 RT 电影数据评估提取的呼吸信号的质量。此外,还评估了选择具有一致呼吸相位的心跳对心功能量化的影响。使用所提出的方法提取的呼吸信号在所有情况下都表现出与参考的高度正相关性,并且与最近提出的方法相比更加稳健。此外,对于右心室 (RV) 功能量化,选择呼气位置的心跳可提高 RT 电影和屏气参考之间的一致性。所提出的方法能够从 RT 心脏电影图像中全自动提取呼吸信号并确定呼吸信号,从而实现准确的心脏功能量化。
To develop an automatic method for selecting heartbeats with consistent respiratory phase to improve accuracy of cardiac function quantification in real-time (RT) cardiac MRI. The respiratory signal is extracted by a principal component analysis method from RT cine images. Then, a two-step procedure is used to determine the directionality (sign) of the respiratory signal. With the motion in a manually selected region-of-interest as reference, the quality of the extracted respiratory signal is assessed using multi-slice RT cine data from eleven volunteers and ten patients. In addition, the impact of selecting heartbeats with consistent respiratory phase on the cardiac function quantification is evaluated. The extracted respiratory signal using the proposed method exhibits a high, positive correlation with the reference in all cases and is more robust compared to a recently proposed method. Also, for right ventricular (RV) function quantification, selecting heartbeats at expiratory position improves agreement between RT cine and breath-held reference. The proposed method enables fully automatic extraction and directionality determinations of respiratory signal from RT cardiac cine images, allowing accurate cardiac function quantification.
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