The efferent projections of the pretectal complex: an autoradiographic and horseradish peroxidase analysis
The efferent projections of the pretectal complex: an autoradiographic and horseradish peroxidase analysis
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顶盖前复合体的传出投射：放射自显影和辣根过氧化物酶分析
DOI：
10.1016/0006-8993(80)91315-3
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发表时间：
1980
期刊：
影响因子：
2.9
通讯作者：
J. K. Harting
中科院分区：
文献类型：
--
作者：
J. T. Weber;J. K. Harting
顺行放射自显影数据显示，神经元内的pretectal复杂的树拥有轴突终止在三个一般类别的目标。首先，有一个主要的同侧下行通路的目标，其中包括：下橄榄复合体的Kooy的背帽，灰质脑桥的背外侧和背内侧区域，中脑网状结构，直接位于背侧和外侧的红核，内侧终核和浅层的上级丘。第二类的目标接收其pretectal输入从一个大的上升束，项目同侧：丘脑的网状核和外侧核，丘脑的齿状回，中央外侧核和旁中央板内核和双侧的腹外侧膝状体核。第三类靶点包括脑神经和在眼球运动中起作用的密切相关的核团。投射到这第三类细胞核的离顶盖前纤维终止于同侧的Darkschewitsch核内，两侧的后连合核和Cajal间质核内，以及对侧的眼神经核和trochiar核的体细胞柱内。在11个顶盖前靶区注射辣根过氧化物酶。这些数据证实并扩展了我们的放射自显影研究结果，表明大多数顶盖前靶点接受来自几个顶盖前核团的输入，并且顶盖前神经元的大小而不是它们所在的细胞群决定了它们轴突的终止位点。
Anterograde autoradiographic data reveal that neurons within the pretectal complex of the tree shrew possess axons which terminate within three general categories of targets. First, there are targets of a major ipsilateral descending pathway which include: the dorsal cap of Kooy of the inferior olivary complex, the dorsolateral and dorsomedial regions of the griseum pontis, the mesencephalic reticular formation which lies immediately dorsal and lateral to the red nucleus, the medial terminal nucleus and the superficial layers of the superior colliculus. A second category of targets receive their pretectal input from a large ascending bundle which projects ipsilaterally to: the reticular and lateral nuclei of the thalamus, the zona incerta, the central lateral and paracentral intralaminar nuclei of the thalamus and bilaterally to the ventral lateral geniculate nucleus. A third category of targets include cranial nerve and closely associated nuclei which play a role in eye movements. Pretectofugal fibers projecting to nuclei in this third category terminate ipsilaterally within the nucleus of Darkschewitsch, bilaterally within the nucleus of the posterior commissure and the interstitial nucleus of Cajal, and contralaterally within the somatic cell column of the oculomotor and trochlear nuclei. There are also commissural projections to contralateral pretectal cell groups.Injections of horseradish peroxidase were placed within 11 pretectal targets. These data, which confirm and extend our autoradiographic findings, show that the majority of pretectal targets receive input from several pretectal nuclei, and that the size of pretectal neurons, rather than the cell groups in which they are located, dictates the termination site(s) of their axons.