Outcomes of Fat Injection Laryngoplasty in Unilateral Vocal Cord Paralysis
Outcomes of Fat Injection Laryngoplasty in Unilateral Vocal Cord Paralysis
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DOI：
10.1001/archoto.2010.42
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发表时间：
2010-05-01
影响因子：
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通讯作者：
Chuang, Hsiu-Feng
中科院分区：
文献类型：
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作者：
Fang, Tuan-Jen;Li, Hsueh-Yu;Chuang, Hsiu-Feng
目的：分析单侧声带麻痹患者脂肪注射喉成形术的疗效。设计：纵向结果评价研究。背景：三级转诊语音中心。患者：在台北市长公纪念医院连续33例单侧声带麻痹患者行自体脂肪注射喉部成形术，术前及术后随访。干预：自体脂肪注射喉成形术。主要结果测量：语音实验室测量、语音结果调查和36项简短健康调查。结果：除整体健康生理功能维度外，术后患者的语音相关主观结局及声学变量均有显著改善（P < 0.05）。与人群正常值相比，患者的平均（SD）分数在36项简短健康调查身体功能维度（80.7[22.3]比90.2[17.4]）和角色功能身体问题（65.0[36.2]比80.2[36.2]）上较差。总体而言，88.9%（24 / 27）的患者对手术满意。结论：脂肪注射喉部成形术在单侧声带麻痹患者的声学和生活质量方面似乎是有效的。这种效果可以持续12个月。
Objective: To analyze outcomes following fat injection laryngoplasty in patients with unilateral vocal cord paralysis.Design: Longitudinal outcomes evaluation study.Setting: Tertiary referral voice center.Patients: Thirty-three consecutive patients with unilateral vocal cord paralysis undergoing autologous fat injection laryngoplasty with preoperative and serial postoperative follow-up at Chang Gung Memorial Hospital, Taipei, Taiwan.Intervention: Autologous fat injection laryngoplasty.Main Outcome Measures: Voice laboratory measurements, Voice Outcome Survey, and 36-item Short Form Health Survey.Results: Except for the physical functioning dimension of global health, voice-related subjective outcomes and acoustic variables of the patients significantly improved after surgery (P < .05). Compared with population norms, the mean (SD) scores of patients were inferior on the 36-item Short Form Health Survey dimensions of physical functioning (80.7 [22.3] vs 90.2 [17.4]) and role functioning physical problems (65.0 [36.2] vs 80.2 [36.2]). Overall, 88.9% (24 of 27) of the patients were satisfied with their surgery.Conclusions: Fat injection laryngoplasty seems to be effective in enhancing acoustic and quality of life outcomes in patients with unilateral vocal cord paralysis. The effect is sustainable over 12 months.