Altered coordination patterns in parkinsonian patients during trunk-assisted prehension.
Altered coordination patterns in parkinsonian patients during trunk-assisted prehension.
复制标题
帕金森病患者在躯干辅助抓握过程中的协调模式发生了改变。
DOI：
10.1016/j.parkreldis.2005.11.008
复制
发表时间：
2006
期刊：
影响因子：
--
通讯作者：
Stelmach,GeorgeE
中科院分区：
文献类型：
--
作者：
Wang,Jinsung;Bohan,Michael;Leis,BertaC;Stelmach,GeorgeE
我们研究了在躯干辅助抓握过程中，帕金森病患者在不同的限制条件下(实验1：触达速度、物体大小、运动幅度；实验2：运动顺序)，运动成分之间的协调性是否受到影响。总体而言，PD患者和对照组对这三个变量的变化反应相似。然而，帕金森病患者在开口形成、终点运动和躯干运动的开始和偏移之间的时间上表现出较少的同步运动。此外，PD患者在确定躯干和手臂对终点运动的相对贡献时，使用了不同于对照组的模式。观察到显著的组间差异，因为对照组倾向于将涉及的运动成分同步在一起，而帕金森病患者则没有表现出这种趋势。这些数据表明，帕金森病患者具有完整的参数化能力，尽管他们作为一个单一单元协调多个神经运动协同作用的能力较弱。
We examined whether coordination between movement components during trunk-assisted prehension was compromised in PD patients in response to varying constraints (experiment 1: reach speed, object size, movement amplitude; experiment 2: movement sequence). In general, both PD patients and controls responded similarly to the changes in these three variables. PD patients, however, demonstrated less synchronized movements in terms of timing between onsets and offsets of aperture formation, endpoint motion and trunk motion. In addition, PD patients used a pattern different from that of controls in specifying the relative contribution of trunk and arm to the endpoint motion. A significant group difference was observed in that controls tended to synchronize the involved movement components together, whereas PD patients did not show such a trend. These data suggest that PD patients have intact parameterization capabilities, although they have a reduced capability to coordinate multiple neuromotor synergies as a single unit.