Phylogenetic study of the species within the family Streptomycetaceae
Phylogenetic study of the species within the family Streptomycetaceae
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DOI：
10.1007/s10482-011-9656-0
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发表时间：
2012-01-01
影响因子：
2.6
通讯作者：
Hatano, K.
中科院分区：
文献类型：
--
作者：
Labeda, D. P.;Goodfellow, M.;Hatano, K.
链霉菌属的种类构成了链霉菌科的绝大多数分类群，是世界各地土壤微生物种群的主要组成部分，多年来一直是广泛分离和筛选的对象，因为它们是具有重要商业和医学意义的次生代谢物的主要来源。链霉菌菌株的分类特征一直是一个挑战，因为学术和工业活动产生的大量描述物种比任何其他微生物属都多。多年来，用于表征的方法经历了几个阶段，从主要基于形态观察的方法，到后来基于标准化表型特征集的数字分类分析的分类，以及最近使用的基因序列的分子系统发育分析。目前的系统发育研究基于16S rRNA基因序列研究了链霉菌科几乎所有已描述的物种(615个分类群)，并阐明了该科的物种多样性，观察到该科包含130个统计支持的分支，以及许多不支持的和单一成员的簇。许多观察到的分支与早期的形态和数值分类研究是一致的，但很明显，该科物种内的16S rRNA基因序列存在足够的变异，不足以允许引导支持的许多单个簇之间的关系的解决。
Species of the genus Streptomyces, which constitute the vast majority of taxa within the family Streptomycetaceae, are a predominant component of the microbial population in soils throughout the world and have been the subject of extensive isolation and screening efforts over the years because they are a major source of commercially and medically important secondary metabolites. Taxonomic characterization of Streptomyces strains has been a challenge due to the large number of described species, greater than any other microbial genus, resulting from academic and industrial activities. The methods used for characterization have evolved through several phases over the years from those based largely on morphological observations, to subsequent classifications based on numerical taxonomic analyses of standardized sets of phenotypic characters and, most recently, to the use of molecular phylogenetic analyses of gene sequences. The present phylogenetic study examines almost all described species (615 taxa) within the family Streptomycetaceae based on 16S rRNA gene sequences and illustrates the species diversity within this family, which is observed to contain 130 statistically supported clades, as well as many unsupported and single member clusters. Many of the observed clades are consistent with earlier morphological and numerical taxonomic studies, but it is apparent that insufficient variation is present in the 16S rRNA gene sequence within the species of this family to permit bootstrap-supported resolution of relationships between many of the individual clusters.