MEAN WALL THICKNESS OF TRABECULAR BONE PACKETS IN HUMAN ILIAC CREST - CHANGES WITH AGE

MEAN WALL THICKNESS OF TRABECULAR BONE PACKETS IN HUMAN ILIAC CREST - CHANGES WITH AGE
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DOI:
10.1007/bf02013227
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发表时间:
1978-01-01
期刊:
CALCIFIED TISSUE RESEARCH
影响因子:
--
通讯作者:
MEUNIER, PJ
MEUNIER, PJ
中科院分区:
其他
文献类型:
--
作者:
LIPS, P;COURPRON, P;MEUNIER, PJ

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在偏振光下测量 36 名正常受试者(14 名女性和 22 名男性)的未脱钙髂嵴骨样本中小梁骨包的平均壁厚度 (MWT)。平均壁厚为49.7±。 8.7 微米,平均年龄 50.9 岁。随着年龄的增长,MWT 显着下降。当附着率为0.72μm/天时,髂骨小梁骨包的平均形成时间为69天。 MWT随年龄的降低对应于基本多细胞单位(BMU)水平的骨形成随着年龄的增长而减少,并且可以部分解释生理性老年性骨质减少。
The mean wall thickness (MWT) of packets of trabecular bone was measured in undecalcified iliac crest bone samples of 36 normal subjects (14 female and 22 male) under polarized light. The mean wall thickness was 49.7 .+-. 8.7 .mu.m at a mean age of 50.9 yr. There existed a significant decrease of MWT with advancing age. With an appositional rate of 0.72 .mu.m/day, the mean formation time of iliac trabecular bone packets is 69 days. The decrease of MWT with age corresponds to a decrease in bone formation at the basic multicellular unit (BMU) level with aging and can partly explain the physiological senile osteopenia.