Advanced Synthetic Materials in Detection Science
Advanced Synthetic Materials in Detection Science
复制标题
检测科学中的先进合成材料
DOI：
10.1039/9781849737074-00075
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发表时间：
2014
期刊：
影响因子：
--
通讯作者：
EL-Sharif H
中科院分区：
文献类型：
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作者：
EL-Sharif H
分子印迹聚合物（MIPs）是一种智能材料，可以选择性地结合具有一定程度化学亲和力的特定分子。分子印迹技术已迅速成为在合成聚合物中标记高特异性和选择性识别位点的有效方法。因此，mip通常被称为塑料抗体或合成受体。多年来，MIPs越来越多地用于制造传感器，1,2用于分离方法，3,4用于蛋白质结晶，5,6和催化。mip是一种高度交联的聚合物网络，具有固有的稳定性和鲁棒性，能够促进其在极端环境中的应用。其功能机制类似于抗体或酶，其检测基于分子和MIP之间的形状、方向和相互作用，就像锁和钥匙一样。3,8,9印迹过程发生在通过原位印迹自组装产生聚合物网络时
Molecularly imprinted polymers (MIPs) are smart materials designed to selectively bind certain molecules with a degree of chemical affinity. Molecular imprinting has rapidly become an effective method of imprinting highly specific and selective recognition sites in synthetic polymers. As such, MIPs have generally been referred to as plastic antibodies or synthetic receptors. Over the years, MIPs have increased in popularity to fabricate sensors, 1, 2 in separation methods, 3, 4 in protein crystallization, 5, 6 and in catalysis. 7 MIPs are highly cross-linked polymer networks that are intrinsically stable, robust, and are able to facilitate their application in extreme environments. The functional mechanism is similar to antibodies or enzymes, where detection is based on shape, orientation, and interaction between the molecule and the MIP, much like a lock and key. 3, 8, 9 The imprinting process occurs when polymer networks are generated by either a self-assembly in situ imprinting