Angiogenesis, vasculogenesis, and induction of healing in chronic wounds.
Angiogenesis, vasculogenesis, and induction of healing in chronic wounds.
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DOI：
10.1177/153857440503900401
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发表时间：
2005-07-01
影响因子：
0.9
通讯作者：
Velazquez, Omaida C
中科院分区：
文献类型：
--
作者：
Bauer, Stephen M;Bauer, Richard J;Velazquez, Omaida C
伤口愈合的关键中心阶段需要伤口基底肉芽组织的新血管形成。在成人中，现在已知新血管形成通过血管生成和血管生成两者发生。了解这两个过程的生物学为患有慢性，不愈合的缺血性伤口的患者提供了有希望的新治疗选择。作者回顾了目前有关血管生成和血管生成过程及其与伤口愈合的关系的文献。
A key central stage of wound healing requires neovascularization of the wound base granulation tissue. In the adult, neovascularization is now known to occur by both angiogenesis and vasculogenesis. Understanding the biology of these 2 processes offers promising new therapeutic options for patients who suffer from chronic, nonhealing ischemic wounds. The authors review the current literature on the processes of angiogenesis and vasculogenesis and how it relates to wound healing.