Blast2GO:: a universal tool for annotation, visualization and analysis in functional genomics research

Blast2GO:: a universal tool for annotation, visualization and analysis in functional genomics research
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DOI:
10.1093/bioinformatics/bti610
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发表时间:
2005-09-15
期刊:
影响因子:
5.8
通讯作者:
Robles, M
Robles, M
中科院分区:
生物学3区
文献类型:
--
作者:
Conesa, A;Götz, S;Robles, M

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这里我们介绍了Blast2GO(B2G),这是一个研究工具,设计的主要目的是实现基于基因本体论(GO)的数据挖掘,对尚未提供GO注释的序列数据进行挖掘。一个应用程序中的B2G关节围棋注释基于统计分析的相似性搜索,并在有向无环图上突出显示。这一工具为非模式物种的功能基因组研究提供了一个合适的平台。B2G是一个直观和交互的桌面应用程序,允许监控和理解整个注释和分析过程。
We present here Blast2GO (B2G), a research tool designed with the main purpose of enabling Gene Ontology (GO) based data mining on sequence data for which no GO annotation is yet available. B2G joints in one application GO annotation based on similarity searches with statistical analysis and highlighted visualization on directed acyclic graphs. This tool offers a suitable platform for functional genomics research in non-model species. B2G is an intuitive and interactive desktop application that allows monitoring and comprehension of the whole annotation and analysis process.