It's time to revise the definition of status epilepticus
It's time to revise the definition of status epilepticus
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DOI：
10.1111/j.1528-1157.1999.tb02000.x
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发表时间：
1999-01-01
期刊：
影响因子：
5.6
通讯作者：
Macdonald, RL
中科院分区：
文献类型：
--
作者：
Lowenstein, DH;Bleck, T;Macdonald, RL
全身性、强直-阵挛性癫痫持续状态是一种常见的神经系统急症，需要及时治疗。诊断通常并不困难，除了那些长时间癫痫发作的患者，他们经常发展出越来越微妙的临床特征（1,2）。在治疗方面，医生们似乎也达成了共识(3)。然而，关于癫痫持续状态有一个主要而持久的难题：它的定义。关于癫痫持续状态精确定义的讨论常常导致一致的结果，即当前的“教科书”定义要么不精确，要么与临床实践不一致，要么两者兼而有之。在这里，我们提出一个修订的系统来定义癫痫持续状态，以解决这些问题。
Generalized, tonic-clonic status epilepticus is well recognized as a common neurologic emergency requiring prompt treatment. The diagnosis is usually not difficult, other than for patients with prolonged seizures, who often develop increasingly subtle clinical features (1, 2). There also appears to be a consensus among physicians regarding treatment (3). Nonetheless, there is a major, persistent dilemma regarding status epilepticus: its definition. Discussions concerning the precise definition of status epilepticus all too often result in agreement that current “textbook” definitions are either imprecise, at odds with clinical practice, or both. Here we propose a revised system for defining status epilepticus that addresses these problems.