Hepatitis B virus, hepatitis C virus and HIV coinfection among people living with HIV/AIDS in Buenos Aires, Argentina.
Hepatitis B virus, hepatitis C virus and HIV coinfection among people living with HIV/AIDS in Buenos Aires, Argentina.
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阿根廷布宜诺斯艾利斯艾滋病毒/艾滋病患者中的乙型肝炎病毒、丙型肝炎病毒和艾滋病毒合并感染。
DOI：
10.1097/olq.0b013e3181d73c0d
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发表时间：
2010
影响因子：
3.1
通讯作者：
Cahn,Pedro
中科院分区：
文献类型：
--
作者：
Laufer,Natalia;Quarleri,Jorge;Bouzas,MaríaB;Juncos,Gerardo;Cabrini,Mercedes;Moretti,Franco;Bolcic,Federico;Fernández-Giuliano,Silvina;Mammana,Lilia;Salomón,Horacio;Cahn,Pedro
自1982年报告首例病例以来，阿根廷的艾滋病毒疫情发生了变化。自1990年代初以来，观察到肠道外获得性感染的人数有所减少，通过无保护的性接触（异性恋和同性恋）传播的人数明显增加，感染艾滋病毒/艾滋病的妇女人数也明显增加。在阿根廷，很少有关于乙肝和丙肝病毒合并感染的流行病学研究。我们在布宜诺斯艾利斯的一家大型诊所进行了这项研究，照顾了3000多名艾滋病患者。在7个月的时间里（2004年9月至2005年3月），所有18岁的艾滋病毒阳性患者都被邀请参加了这项研究，这些患者在我们的单位接受了随访，并在阿根廷国家艾滋病参考中心（CNRS）接受了HIV病毒载量（VL）的预定控制。该研究得到了Fernández医院伦理委员会的批准。患者在知情的情况下同意参与这项研究。600名受试者被要求参加这项研究，593人接受了这项研究。研究人群：65.6%为男性，64%为20 - 40岁的年轻人。性接触是HIV感染的主要途径（70%）。在593份样本中，52%（308份）显示乙型或丙型肝炎合并感染的血清学标志物（HBcAb/HBsAg/anti-HCV）阳性结果。合并感染率和受试者特征见表1。
The HIV epidemic in Argentina has changed since the first case was reported in 1982. Since the beginning of the 1990s, a decrease in the number parenterally acquired infections has been observed, with a marked increase in transmission through unprotected sexual contact (heterosexual and homosexual), and in the number of women living with HIV/AIDS. 1 Few prevalence studies have addressed the hepatitis B and C virus coinfection in Argentina. We performed this study in a large single clinic in Buenos Aires, taking care of more than 3000 HIV patients. During a 7-month period (September 2004 to March 2005), all HIV-positive patients 18 years old, who were followed up at our unit and who had their scheduled controls for HIV viral load (VL) at the Argentinean National Reference Centre for AIDS (CNRS), were invited to participate in the study. The study was approved by the Fernández Hospital Ethics Committee. Patients gave their informed consent to be included in the study. Six hundred subjects were asked to enter the study, and 593 accepted.Studied population: 65.6% males, 64% young adults between 20 and 40 years old. The main route of HIV infection was through sexual contact (70%). Of the 593 samples, 52%(n 308) showed positive results for serological markers (HBcAb/HBsAg/anti-HCV) for hepatitis B or C coinfection. Coinfection rates and subjects characteristics are described in Table 1.