Comparative effectiveness and cost-effectiveness of antiretroviral therapy and pre-exposure prophylaxis for HIV prevention in South Africa
Comparative effectiveness and cost-effectiveness of antiretroviral therapy and pre-exposure prophylaxis for HIV prevention in South Africa
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DOI：
10.1186/1741-7015-12-46
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发表时间：
2014-03-17
期刊：
影响因子：
9.3
通讯作者：
Bendavid, Eran
中科院分区：
文献类型：
--
作者：
Alistar, Sabina S.;Grant, Philip M.;Bendavid, Eran
Background: Antiretroviral therapy (ART) and oral pre-exposure prophylaxis (PrEP) are effective in reducing HIV transmission in heterosexual adults. The epidemiologic impact and cost-effectiveness of combined prevention approaches in resource-limited settings remain unclear.Methods: We develop a dynamic mathematical model of the HIV epidemic in South Africa's adult population. We assume ART reduces HIV transmission by 95% and PrEP by 60%. We model two ART strategies: scaling up access for those with CD4 counts
