Review of convergent beam tomography in single photon emission computed tomography.

Review of convergent beam tomography in single photon emission computed tomography.
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DOI:
10.1088/0031-9155/37/3/002
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发表时间:
1992-03
影响因子:
3.5
通讯作者:
G. Gullberg;G. L. Zeng;F. Datz;P. Christian;C. Tung;H. Morgan
G. Gullberg;G. L. Zeng;F. Datz;P. Christian;C. Tung;H. Morgan
中科院分区:
工程技术2区
文献类型:
--
作者:
G. Gullberg;G. L. Zeng;F. Datz;P. Christian;C. Tung;H. Morgan

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会聚束单光子发射计算机断层扫描(SPECT)的研究正在积极进行,以评估其临床潜力。扇形射束、锥形射束、针孔和准直器正与具有大晶体面积的旋转伽马相机一起使用,以增加诸如甲状腺、大脑或心脏的小器官的发射和透射计算机断层摄影的灵敏度。使用新的多探测器SPECT系统,会聚束几何结构提供了同时获得量化心脏中放射性药物分布摄取所需的发射和透射数据的能力。SPECT会聚束几何结构的发展需要硬件和软件的集成。在考虑硬件时,用于锥束层析成像的最佳检测器系统是满足数据充分条件的系统,对于该条件,扫描轨迹与穿过重建的感兴趣区域的任何平面相交。然而,算法的主要发展一直是针对单平面轨道采集数据不足的情况。这些算法的发展使得这项技术的初步评估成为可能,并且脑和心脏的成像显示出锥形束断层扫描的临床应用的巨大潜力。目前,重要的研究活动是追求满足数据充分性条件并且可以在临床SPECT系统上容易且廉价地实施的用于数据采集的算法的开发。
Investigation of convergent-beam single photon emission computed tomography (SPECT) is actively being pursued to evaluate its clinical potentials. Fan-beam, cone-beam, pin-hole and astigmatic collimators are being used with rotating gamma cameras having large crystal areas, to increase the sensitivity for emission and transmission computed tomography of small organs such as the thyroid, brain or heart. With new multi-detector SPECT systems, convergent-beam geometry offers the ability to simultaneously obtain emission and transmission data necessary to quantify uptake of radiopharmaceutical distributions in the heart. The development of convergent-beam geometry in SPECT requires the integration of hardware and software. In considering hardware, the optimum detector system for cone-beam tomography is a system that satisfies the data sufficiency condition for which the scanning trajectory intersects any plane passing through the reconstructed region of interest. However, the major development of algorithms has been for the data insufficient case of single planar orbit acquisitions. The development of these algorithms have made possible the preliminary evaluation of this technology and the imaging of brain and heart are showing significant potential for the clinical application of cone-beam tomography. Presently, significant research activity is pursuing the development of algorithms for data acquisitions that satisfy the data sufficiency condition and that can be implemented easily and inexpensively on clinical SPECT systems.