Evaluation of the new AJCC/UICC staging system for hepatocellular carcinoma after hepatic resection in Chinese patients.
Evaluation of the new AJCC/UICC staging system for hepatocellular carcinoma after hepatic resection in Chinese patients.
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DOI：
10.1016/s1055-3207(02)00086-8
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发表时间：
2003-01-01
影响因子：
1.9
通讯作者：
Fan, Sheung-Tat
中科院分区：
文献类型：
--
作者：
Poon, Ronnie Tung-Ping;Fan, Sheung-Tat
肝切除术被认为是肝癌的首选治疗方法，然而，肝癌切除术后患者的预后差异很大，这取决于临床病理特征。美国癌症联合委员会（AJCC）/国际抗癌联盟（UICC）肿瘤淋巴结转移（TNM）分期系统被广泛用于评估HCC患者。目前HCC的TNM分期使用肿瘤的病理特征，包括肿瘤结节的大小、数量和位置，血管侵犯的存在，脏层腹膜穿孔和邻近器官的侵犯作为T分期的标准。最近，已经提出了用于HCC的简化AJCC/UICC分期。此外，日本肝癌研究小组提出了一种新的简化分期系统，该系统基于肿瘤结节的数量、肿瘤的大小以及侵入门静脉、肝静脉或胆管。本文评估了新AJCC/UICC TNM分期和新日本分期在一个大型队列中的预后价值，这些患者在一个单一机构接受了肝切除术治疗HCC。
Hepatic resection is considered the treatment of choice for HCC; however, the prognosis of patients after resection of HCC varies widely, depending on the clinicopathologic features. The American Joint Committee on Cancer (AJCC)/International Union Against Cancer (UICC) tumor-node-metastasis (TNM) staging system is widely used evaluating patients with HCC. The current TNM staging for HCC uses pathologic characteristics of tumors, including size, number and location of tumor nodules, presence of vascular invasion, perforation of visceral peritoneum, and invasion of adjacent organs as criteria for T staging. Recently, a simplified AJCC/UICC staging for HCC has been proposed. In addition, the Liver Cancer Study Group of Japan proposed a new simplified staging system based on number of tumor nodules, size of tumors, and invasion into the portal vein, hepatic vein, or bile duct. This article evaluates the prognostic value of the new AJCC/UICC TNM staging and the new Japanese staging in a large cohort of Chinese patients who underwent hepatectomy for HCC in a single institution.