Improvements of efficiency and regioselectivity in the iridium(I)-catalyzed aromatic C-H silylation of arenes with fluorodisilanes
Improvements of efficiency and regioselectivity in the iridium(I)-catalyzed aromatic C-H silylation of arenes with fluorodisilanes
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DOI：
10.1021/om050968
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发表时间：
2006-12-18
期刊：
影响因子：
2.8
通讯作者：
Miyaura, Norio
中科院分区：
文献类型：
--
作者：
Saiki, Takeaki;Nishio, Yukihiro;Miyaura, Norio
芳烃（10 当量）与 1,2-二仲丁基-1,1,2,2-四氟乙硅烷的芳族 C-H 甲硅烷基化反应在辛烷中于 120°C 下，在由 1/2[Ir(OMe)(COD)](2) 生成的催化量的铱 (I) 络合物 (3.0 mol%) 存在下进行 2,9-二异丙基-1,10-菲咯啉。许多芳烃的反应导致以高产率和优异的区域选择性形成相应的芳基氟硅烷。
The aromatic C-H silylation of arenes (10 equiv) with 1,2-di-sec-butyl-1,1,2,2-tetrafluorodisilane was carried out in octane at 120 degrees C in the presence of a catalytic amount of iridium(I) complexes (3.0 mol %) generated from 1/2[Ir(OMe)(COD)](2) and 2,9-diisopropyl-1,10-phenanthroline. The reactions of many arenes resulted in the formation of corresponding arylfluorosilanes in high yields with excellent regioselectivities.