Probiotics and prevention of Clostridium difficile infection
Probiotics and prevention of Clostridium difficile infection
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DOI：
10.1016/j.anaerobe.2016.12.007
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发表时间：
2017-06-01
期刊：
影响因子：
2.3
通讯作者：
McFarland, L. V.
中科院分区：
文献类型：
--
作者：
Goldstein, E. J. C.;Johnson, S. J.;McFarland, L. V.
益生菌作为预防艰难梭菌感染（CDI）的辅助措施的作用一直存在争议。然而，越来越多的证据表明它们在 CDI 的一级预防中发挥着作用。回顾了这一争议的要点，并讨论了益生菌的作用机制、价值和成本效益，重点关注三种制剂：布拉酵母菌、鼠李糖乳杆菌 GG 以及嗜酸乳杆菌 CL1285、干酪乳杆菌 LBC8OR、鼠李糖乳杆菌 CLR2 (Bio-K+) 的组合。 (C) 2016 Elsevier Ltd. 保留所有权利。
The role of probiotics as adjunctive measures in the prevention of Clostridium difficile infection (CDI) has been controversial. However, a growing body of evidence has suggested that they have a role in primary prevention of CDI. Elements of this controversy are reviewed and the proposed mechanisms of action, the value and cost effectiveness of probiotics are addressed with a focus on three agents, Saccharomyces boulardii, Lactobacillus rhamnosus GG and the combination of Lactobacillus acidophilus CL1285, Lactobacillus casei LBC8OR, Lactobacillus rhamnosus CLR2 (Bio-K+). (C) 2016 Elsevier Ltd. All rights reserved.