Antigen-detection in the diagnosis of SARS-CoV-2 infection using rapid immunoassays
Antigen-detection in the diagnosis of SARS-CoV-2 infection using rapid immunoassays
复制标题
使用快速免疫分析进行抗原检测诊断 SARS-CoV-2 感染
DOI：
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发表时间：
2020
期刊：
影响因子：
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通讯作者：
W. Organization
中科院分区：
文献类型：
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作者：
W. Organization
一种新的COVID-19检测技术已经问世，它比目前推荐的核酸扩增检测（NAAT）更简单、更快速，这种方法依赖于使用侧流免疫测定法直接检测鼻拭子和其他呼吸道分泌物中的SARS-CoV-2病毒蛋白（也称为RDT），在30分钟内给出结果。尽管这些抗原检测RDT（Ag-RDT）的灵敏度远低于NAAT，但它们提供了快速，在适当的环境中廉价和早期发现最具传染性的COVID病例认识到目前关于这些检测的性能和操作效用的数据不足，本文件旨在为各国考虑纳入COVID疫情管理计划提供指导
A new technology for COVID-19 detection has become available that is much simpler and faster to perform that currently-recommended nucleic acid amplification tests (NAAT), like PCR This method relies on direct detection of SARS-CoV-2 viral proteins in nasal swabs and other respiratory secretions using a lateral flow immunoassay (also called an RDT) that gives results in 30 minutes Though these antigen detection RDTs (Ag-RDTs) are substantially less sensitive than NAAT, they offer the possibility of rapid, inexpensive and early detection of the most infectious COVID cases in appropriate settings Acknowledging the inadequacy of current data on the performance and operational utility of these tests, this document seeks to provide guidance to countries on considerations for integration into COVID outbreak management programs