N-ACETYLCOLCHINOL - STRUCTURE AND HYDROGEN-BONDING IN A BENZENOID COLCHICINE ANALOG
N-ACETYLCOLCHINOL - STRUCTURE AND HYDROGEN-BONDING IN A BENZENOID COLCHICINE ANALOG
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DOI：
10.1016/0006-291x(78)91014-8
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发表时间：
1978-01-01
影响因子：
3.1
通讯作者：
LESSINGER, L
中科院分区：
文献类型：
--
作者：
MARGULIS, TN;LESSINGER, L
n -乙酰秋水仙醇是秋水仙碱的苯类衍生物，在空间群p21中结晶为一水合物，a = 14.334, b = 7.848, c = 17.634 Å；β = 100.6°，z = 4。根据3978次x射线反射确定了结构，并将其细化为R = 0.039。分子形状与秋水仙碱相似，晶体上有氢键和疏水区。
N-Acetylcolchinol, a benzenoid derivative of colchicine, crystallizes as the monohydrate in space group P21with a = 14.334, b = 7.848, c = 17.634 Å; β = 100.6°, Z = 4. The structure was determined from 3978 X-ray reflections and refined to R = 0.039. The molecular shape is like that of colchicine and the crystal shows hydrogen-bonding and hydrophobic regions.