Multidimensional micro- and nano-printing technologies: general discussion.
Multidimensional micro- and nano-printing technologies: general discussion.
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多维微米和纳米印刷技术：一般讨论。
DOI：
10.1039/c9fd90061f
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发表时间：
2019
影响因子：
3.4
通讯作者：
Azevedo HS
中科院分区：
文献类型：
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作者：
Azevedo HS
亚当布伦瑞克首先对彼得·西伯格的论文进行了讨论：在许多涉及糖萼结合的系统中，会发生多种不同的蛋白质-受体相互作用。这些可能涉及从单一蛋白质到简单类型的糖的多价相互作用，或者可能涉及与不同类型的糖结合以实现所需的响应。你如何想象下一代的聚糖微阵列可以通过在阵列的相同特征内打印具有编程间距和比例的不同材料来询问这些相互作用？
Adam Braunschweig opened the discussion of the paper by Peter Seeberger: In many systems that involve binding in the glycocalyx, there are o en multiple different protein–receptor interactions that occur. These may involve multivalent interactions from a single protein to a simple type of sugar, or may involve binding to different types of sugars to achieve a desired response. How do you imagine that the next generation of glycan microarrays can be built to interrogate these interactions by possibly printing different materials with programmed spacings and ratios within the same feature of an array?