Microfluidic-SERS devices for one shot limit-of-detection.
Microfluidic-SERS devices for one shot limit-of-detection.
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DOI:
10.1039/c4an00357h
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发表时间:
2014-07-07
期刊:
影响因子:
--
通讯作者:
Haynes CL
中科院分区:
文献类型:
--
作者:
Kim D;Campos AR;Datt A;Gao Z;Rycenga M;Burrows ND;Greeneltch NG;Mirkin CA;Murphy CJ;Van Duyne RP;Haynes CL
Microfluidic sensing platforms facilitate parallel, low sample volume detection using various optical signal transduction mechanisms. Herein, we introduce a simple mixing microfluidic device, enabling serial dilution of introduced analyte solution that terminates in five discrete sensing elements. We demonstrate the utility of this device with on-chip fluorescence and surface-enhanced Raman scattering (SERS) detection of analytes, and we demonstrate device use both when combined with a traditional inflexible SERS substrate and with SERS-active nanoparticles that are directly incorporated into microfluidic channels to create a flexible SERS platform. The results indicate, with varying sensitivities, that either flexible or inflexible devices can be easily used to create a calibration curve and perform a limit of detection study with a single experiment.
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影响因子:
15
作者:
Cao, YC;Jin, RC;Mirkin, CA
通讯作者:
Mirkin, CA
影响因子:
3.9
作者:
Hulteen, John C.;Young, Matthew A.;Van Duyne, Richard P.
通讯作者:
Van Duyne, Richard P.
影响因子:
--
作者:
Murphy, Catherine J.
通讯作者:
Murphy, Catherine J.
影响因子:
2.5
作者:
Giesfeldt, KS;Connatser, RM;Sepaniak, MJ
通讯作者:
Sepaniak, MJ
DOI:
10.1007/978-0-387-70715-0_10
发表时间:
2010-01-01
期刊:
NEUROVASCULAR NEUROPSYCHOLOGY
影响因子:
--
作者:
Lim, Chun;Alexander, Michael
通讯作者:
Alexander, Michael