Volume magnetic susceptibility design and hardness of Au-Ta alloys and Au-Nb alloys for MRI-compatible biomedical applications
Volume magnetic susceptibility design and hardness of Au-Ta alloys and Au-Nb alloys for MRI-compatible biomedical applications
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用于 MRI 兼容生物医学应用的 Au-Ta 合金和 Au-Nb 合金的体积磁化率设计和硬度
DOI：
10.1088/2057-1976/aa5449
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发表时间：
2017
影响因子：
1.4
通讯作者：
Kenichi Hamada
中科院分区：
文献类型：
--
作者：
Shihoko Inui;Emi Uyama;Kenichi Hamada
研究了Au-Ta合金和Au-Nb合金的体积磁化率（χ v）和维氏硬度（HV），以作为磁共振成像（MRI）兼容的医用合金。Au-Ta合金的χ v与相组成无关，而与合金成分有关。因此，热处理对Au-Ta合金的χ v几乎没有影响，只有Ta含量接近15的合金才可能与MRI兼容。相反，Au-Nb合金的χ v取决于相组成。因此，合金成分和热处理都可以用来广泛控制Au-Nb合金的χ v，并且通过热处理优化χ v可以使Au-xNb合金（x≥ 6.8）与MRI兼容。即使在热处理后，Au-15 Ta合金的HV也小于纯Ti的HV，而MRI兼容的Au-Nb合金的HV在热处理后可能高于纯Ti的HV。Au-Nb合金在800 ℃热处理后的饱和χ v值与基于混合物规则的合金的χ v是合金的每个相的平均χ v的假设是相容的。这一假设支持通过控制合金成分和热处理来定制χ v。
The volume magnetic susceptibility (χ v) and Vickers hardness (HV) of Au–Ta and Au–Nb alloys were investigated for use as magnetic resonance imaging (MRI)-compatible alloys for biomedical applications. χ v of the Au–Ta alloys did not depend on the phase constitution but did depend on the alloy composition. Therefore, heat treatment hardly affected χ v of the Au–Ta alloys, and only alloys with Ta contents near 15 were possibly MRI-compatible. In contrast, χ v of the Au–Nb alloys depended on the phase constitution. Therefore, both the alloy composition and heat treatment can be used to widely control χ v of Au–Nb alloys, and Au–xNb alloys (x≥ 6.8) can be made MRI-compatible by optimizing χ v using heat treatment. HV of the Au–15Ta alloy was smaller than that of pure Ti even after heat treatment, whereas HV of the MRI-compatible Au–Nb alloys was possibly higher than that of pure Ti after heat treatment. The saturated χ v values of the Au–Nb alloys after heat treatment at 800 C are compatible with the hypothesis that χ v of an alloy is the average χ v of each phase of the alloy based on the rule of mixtures. This hypothesis supports the tailoring of χ v by controlling the alloy composition and heat treatment.