CENTRAL-NERVOUS-SYSTEM NEURONS LABELED FOLLOWING THE INJECTION OF PSEUDORABIES VIRUS INTO THE RAT URINARY-BLADDER
CENTRAL-NERVOUS-SYSTEM NEURONS LABELED FOLLOWING THE INJECTION OF PSEUDORABIES VIRUS INTO THE RAT URINARY-BLADDER
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DOI：
10.1016/0304-3940(92)90281-b
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发表时间：
1992-08-31
影响因子：
2.5
通讯作者：
MISELIS, RR
中科院分区：
文献类型：
--
作者：
NADELHAFT, I;VERA, PL;MISELIS, RR
Pseudorabies virus was injected into the wall of the urinary bladder and, following incubation times of 2, 3 and 4 days, central nervous tissue was processed immunohistochemically for the presence of virus. Longer incubation times resulted in more extensive spread of the virus. Infected neurons were initially found in the spinal cord (mainly lumbosacral) and, after longer survival times, in raphe nuclei, reticular area, pontine micturition center. locus coeruleus, red nucleus, hypothalamus. preoptic. and cortical areas. These data define a multisynaptic circuit of neurons whose ultimate output influences urinary bladder function.
