The effect of composition on mechanical properties of brushite cements
The effect of composition on mechanical properties of brushite cements
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DOI：
10.1016/j.jmbbm.2013.08.024
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发表时间：
2014-01-01
影响因子：
3.9
通讯作者：
Engqvist, Hakan
中科院分区：
文献类型：
--
作者：
Engstrand, Johanna;Persson, Cecilia;Engqvist, Hakan
由于透钙磷石水泥具有快速的凝固反应、良好的生物学性能和易于获得的起始材料，作为骨替代材料在透钙磷石水泥领域得到了广泛的研究。然而，透钙磷石水泥的快速凝结由于凝结过程中晶体压实度差而导致其固有的机械性能较低。为了改善这一点，在水泥浆中添加了许多添加剂，例如柠檬酸、焦磷酸盐和乙醇酸，以延缓晶体生长。此外，当使用正确的量时，加入填充材料可以改善机械性能。在本研究中，研究了焦磷酸二氢二钠和柠檬酸这两种缓凝剂的添加以及 β-TCP 填料颗粒的添加对透钙磷石水泥机械性能的影响。结果表明，添加少量填料（最多 10%）即可对机械性能产生很大影响。此外，在液相中添加柠檬酸可以使用较低的液粉比（LIP），这会强烈影响水泥的强度。发现一水合磷酸一钙和β-磷酸三钙摩尔比为45:55、L/P为0.25mVg以及液相中柠檬酸浓度为0.5M的组合物具有最大压缩强度(41.8MPa)。 (C) 2013 作者。由爱思唯尔有限公司出版。保留所有权利。
Due to a fast setting reaction, good biological properties, and easily available starting materials, there has been extensive research within the field of brushite cements as bone replacing material. However, the fast setting of brushite cement gives them intrinsically low mechanical properties due to the poor crystal compaction during setting. To improve this, many additives such as citric acid, pyrophosphates, and glycolic acid have been added to the cement paste to retard the crystal growth. Furthermore, the incorporation of a filler material could improve the mechanical properties when used in the correct amounts. In this study, the effect of the addition of the two retardants, disodium dihydrogen pyrophosphate and citric acid, together with the addition of beta-TCP filler particles, on the mechanical properties of a brushite cement was investigated. The results showed that the addition of low amounts of a filler (up to 10%) can have large effects on the mechanical properties. Furthermore, the addition of citric acid to the liquid phase makes it possible to use lower liquid-to-powder ratios (LIP), which strongly affects the strength of the cements. The maximal compressive strength (41.8 MPa) was found for a composition with a molar ratio of 45:55 between monocalcium phosphate monohydrate and beta-tricalcium phosphate, an L/P of 0.25 mVg and a citric acid concentration of 0.5 M in the liquid phase. (C) 2013 The Authors. Published by Elsevier Ltd. All rights reserved.