Accuracy of self-reported cancer treatment data in young breast cancer survivors
Accuracy of self-reported cancer treatment data in young breast cancer survivors
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DOI：
10.1186/s41687-019-0114-5
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发表时间：
2019-05-01
影响因子：
2.7
通讯作者：
Ruddy, Kathryn J.
中科院分区：
文献类型：
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作者：
Gast, Kelly C.;Cathcart-Rake, Elizabeth J.;Ruddy, Kathryn J.
癌症治疗的患者报告有时用于肿瘤学研究和临床，当医疗记录不可用时。我们的目的是评估在这种情况下患者回忆的准确性。材料和方法参与者是通过电子邮件请求从苏珊博士爱研究基金会妇女军寻求妇女诊断为乳腺癌的年龄在50岁以下，在过去的十年内，自我报告已接受化疗。在知情同意后，参与者接受了一项基于网络的调查，询问了接受的化疗和内分泌治疗的使用和类型。对病历进行了审查，差异定义为患者报告的药物类别与病历中记录的不同，未报告记录的药物类别，或回答“不知道”。“结果在171名合格的参与者中，102人（60%）完成了问卷调查和医疗记录。诊断时的中位年龄为41岁（范围25-49），诊断后的中位时间为65.5个月（范围7-131）。92%的人完成了大学学业。接受化疗的记录在100%的这些自我报告化疗个人史的女性的病历中，关于接受内分泌治疗的一致性也为98%（是与否）。然而，29%的患者在化疗类型方面存在差异。自诊断以来的时间并没有增加差异的可能性。结论高学历的年轻女性诊断乳腺癌超过五年前准确报告是否接受广泛的系统治疗类别。但是，关于特定药物的自我报告应通过病历审查予以确认。
Background Patient-reports of cancer treatments are sometimes used in oncology research and clinically when medical records are unavailable. We aimed to evaluate the accuracy of patient recall in this setting. Materials and methods Participants were recruited through an email request from the Dr. Susan Love Research Foundation Army of Women seeking women diagnosed with breast cancer under age 50 and within the past ten years, self-reporting to have been treated with chemotherapy. After informed consent, participants received a web-based survey that inquired about use of and type of chemotherapy and endocrine therapy received. Medical records were reviewed, and discrepancies were defined as patient-report of a different class of drug than documented in the medical record, failing to report a documented class of drug, or responding "don't know." Results Of 171 eligible participants, completed questionnaires and medical records were available for 102 (60%). Median age at diagnosis was 41 years (range 25-49), and median time from diagnosis was 65.5 months (range 7-131). Ninety-two percent had completed college. Receipt of chemotherapy was documented in the medical records of 100% of these women who self-reported a personal history of chemotherapy, and there was also 98% concordance regarding receipt of endocrine therapy (yes vs. no). However, discrepancies were identified in 29% of patients regarding chemotherapy types. Time since diagnosis did not increase the likelihood of discrepancies. Conclusion Highly educated young women diagnosed with breast cancer more than five years prior accurately report whether or not they received broad systemic treatment categories. However, self-reports regarding specific drugs should be confirmed by medical record review.