MAPPING OF THE FUNCTIONAL ACTIVE-SITE OF BAEYER-VILLIGERASES BY SUBSTRATE ENGINEERING
MAPPING OF THE FUNCTIONAL ACTIVE-SITE OF BAEYER-VILLIGERASES BY SUBSTRATE ENGINEERING
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DOI：
10.1039/c39950000729
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发表时间：
1995-04-07
影响因子：
--
通讯作者：
WRIGHT, MA
中科院分区：
文献类型：
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作者：
KELLY, DR;KNOWLES, CJ;WRIGHT, MA
提出了一个酶催化Baeyer-Villiger反应的活性位点模型，并通过三环酮6的转化进行了验证; Baeyer-Villiger反应（和Baeyer-Villiger酶）根据羟基过氧化物中间体的立体化学进行了分类。
An active sits model for enzyme catalysed Baeyer-Villiger reactions is proposed and validated by transformation of the tricyclic ketone 6; Baeyer-Villiger reactions (and Baeyer-Villigerases) are classified by the stereochemistry of the hydroxyperoxide intermediate.