Expression of keratin proteins in deeply invasive basal and squamous cell carcinoma: an immunohistochemical study.
Expression of keratin proteins in deeply invasive basal and squamous cell carcinoma: an immunohistochemical study.
复制标题
角蛋白在深部浸润性基底细胞癌和鳞状细胞癌中的表达：一项免疫组织化学研究。
DOI：
10.1111/j.1524-4725.1987.tb03951.x
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发表时间：
1987
期刊：
影响因子：
--
通讯作者：
Robinson,JK
中科院分区：
文献类型：
--
作者：
Robinson,JK
某些类型角蛋白的表达与细胞成熟和分化有关。在细胞转化和肿瘤发展过程中，中间纤维角蛋白的细胞特异性在很大程度上是保守的。利用这一点，我们利用单克隆抗角蛋白免疫组织化学技术来检查基底细胞癌和鳞状细胞癌，因为它们变得深度侵袭。
The expression of certain classes of keratin is associated with cell maturation and differentiation. During cell transformation and tumor development, the cell specificity of intermediate filament, keratin, is largely conserved. Taking advantage of this, we utilized monoclonal antikeratin immunohistochemical techniques to examine basal and squamous cell carcinomas as they became deeply invasive.