Air-Stable Triazine-Based Ni(II) PNP Pincer Complexes As Catalysts for the Suzuki-Miyaura Cross-Coupling
Air-Stable Triazine-Based Ni(II) PNP Pincer Complexes As Catalysts for the Suzuki-Miyaura Cross-Coupling
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DOI：
10.1021/acs.orglett.6b01398
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发表时间：
2016-07-01
期刊：
影响因子：
5.2
通讯作者：
Kirchner, Karl
中科院分区：
文献类型：
--
作者：
Mastalir, Matthias;Stoeger, Berthold;Kirchner, Karl
描述了基于2，4-二氨基三嗪骨架的空气稳定、热稳定和良好定义的阳离子Ni（II）PNP钳形络合物。这些络合物是用于广泛的芳基、杂芳基（包括苯并恶唑、噻唑、吡啶、嘧啶、噻唑）、伯和仲烷基卤化物和拟卤化物与不同有机硼酸酯试剂的Suzuki-Miyaura交叉偶联的活性催化剂，提供优异至良好的分离产率。中性去质子化配合物似乎在催化过程中起着关键作用。
Air-stable, thermally robust, and well-defined cationic Ni(II) PNP pincer complexes based on the 2,4-diaminotriazine scaffold are described. These complexes are active catalysts for the Suzuki-Miyaura cross-coupling of a wide range of aryl, heteroaryl (including benzoxazole, thiazole, pyridine, pyrimidine, thiazole), primary and secondary alkyl halides, and pseudohalides with different organoboronate reagents giving excellent to good isolated yields. Neutral deprotonated complexes seem to play a key role in the catalytic process.