COGNITIVE-FUNCTIONING AND POSITIVE AND NEGATIVE SYMPTOMS IN SCHIZOPHRENIA
COGNITIVE-FUNCTIONING AND POSITIVE AND NEGATIVE SYMPTOMS IN SCHIZOPHRENIA
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DOI：
10.1016/0920-9964(91)90039-t
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发表时间：
1991-09-01
影响因子：
4.5
通讯作者：
MATICKATYNDALE, E
中科院分区：
文献类型：
--
作者：
ADDINGTON, J;ADDINGTON, D;MATICKATYNDALE, E
本研究检查了精神分裂症患者在各种认知测量方面的表现，以探讨精神分裂症症状与认知表现之间的关系。蒙特利尔神经学研究所开发的韦克斯勒成人智力量表和一系列神经心理学测试对 38 名住院的重病精神分裂症患者进行了测试。患者使用 DSM III 标准进行诊断。阴性症状用 SANS 评估，阳性症状用 SAPS 评估。在 6 个月的随访期间，对该样本重新进行认知测试和症状评定量表。分析显示，在这两个时期，认知缺陷更可能与高阴性症状评级相关，而不是与阳性症状相关。只有某些测试在随访期间显示出显着改善。此外，认知功能的改善与积极症状的改善有关，但与消极症状的改善无关。
The present study examined schizophrenics' performance on a variety of cognitive measures in order to explore the relationship between schizophrenic symptoms and cognitive performance. The Wechsler Adult Intelligence Scale and a battery of neuropsychological tests, developed at the Montreal Neurological Institute, were administered to 38 acutely ill, hospitalized schizophrenics. Patients were diagnosed using DSM III criteria. Negative symptoms were assessed with the SANS and positive symptoms with the SAPS. Both the cognitive tests and the symptom rating scales were re-administered to this sample at a 6 month follow-up period. Analyses revealed that, at both time periods cognitive deficits were more likely to be associated with high negative symptom ratings than with positive symptoms. Only certain tests showed significant improvement at the follow-up period. Furthermore, improved cognitive functioning was related to an improvement in positive, but not negative, symptoms.