Ebola hemorrhagic fever and pregnancy
Ebola hemorrhagic fever and pregnancy
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DOI：
10.1086/514289
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发表时间：
1999-02-01
影响因子：
6.4
通讯作者：
Muyembe-Tamfum, JJ
中科院分区：
文献类型：
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作者：
Mupapa, K;Mukundu, W;Muyembe-Tamfum, JJ
在(刚果民主共和国)Kikwit总医院隔离病房住院的105名埃博拉出血热妇女中，有15人(14%)怀孕。在10名妇女(66%)中，怀孕以流产告终。在其中3人中，进行了刮宫，所有3人都接受了表面上健康的人的输血。一名妇女早产死产。四名孕妇在怀孕的最后三个月期间死亡。所有女性都出现了严重出血。只有1人活了下来；她在闭经8个月后因不完全流产而进行了刮宫手术。埃博拉出血热孕妇的死亡率(95.5%)略高于基奎特埃博拉疫情期间观察到的总死亡率(77%；245/316感染者)，但并不显著。
Fifteen (14%) of 105 women with Ebola hemorrhagic fever hospitalized in the isolation unit of the Kikwit General Hospital (Democratic Republic of the Congo) were pregnant. In 10 women (66%) the pregnancy ended with an abortion. In 3 of them, a curettage was performed, and all 3 received a blood transfusion from an apparently healthy person. One woman was prematurely delivered of a stillbirth. Four pregnant women died during the third trimester of their pregnancy. All women presented with severe bleeding. Only 1 survived; she had a curettage because of an incomplete abortion after 8 months of amenorrhea. The mortality among pregnant women with Ebola hemorrhagic fever (95.5%) was slightly but not significantly higher than the overall mortality observed during the Ebola epidemic in Kikwit (77%; 245/316 infected persons).