Brain cell proliferation in adult rats after irradiation with nonequilibrium atmospheric pressure plasma
Brain cell proliferation in adult rats after irradiation with nonequilibrium atmospheric pressure plasma
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DOI：
10.35848/1882-0786/ac03c1
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发表时间：
2021-06
影响因子：
2.3
通讯作者：
M. Yamato;Y. Tamura;Hiromasa Tanaka;K. Ishikawa;Y. Ikehara;M. Hori;Y. Kataoka
中科院分区：
文献类型：
--
作者：
M. Yamato;Y. Tamura;Hiromasa Tanaka;K. Ishikawa;Y. Ikehara;M. Hori;Y. Kataoka
Nonequilibrium atmospheric pressure plasma (NEAPP) has the potential for a wide range of medical applications, including wound healing, blood coagulation, and malignant cell apoptosis. However, its effect on the mammalian central nervous system remains unclear. We studied histological changes in the cerebral cortex of adult rats, following irradiation of the brain surface with NEAPP. NEAPP irradiation made three laminar tissue structures and induced high proliferation of brain-resident immature cells as well as bone marrow-derived cells. These observations indicate that NEAPP irradiation induced rearrangement of cellular and tissue organization, including cell proliferation in the central nervous system in vivo.
