Prevalence and predictors of osteopenia and osteoporosis in adults with Type 1 diabetes
Prevalence and predictors of osteopenia and osteoporosis in adults with Type 1 diabetes
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DOI：
10.1111/j.1464-5491.2008.02608.x
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发表时间：
2009-01-01
影响因子：
3.5
通讯作者：
Davis, T. M. E.
中科院分区：
文献类型：
--
作者：
Hamilton, E. J.;Rakic, V.;Davis, T. M. E.
确定成人1型糖尿病患者骨质减少和骨质疏松的患病率和生化/激素决定因素。102例年龄在20-71岁的1型糖尿病患者（52名女性，50名男性）接受了骨代谢生化/激素标志物的横断面评估，并使用双能x线骨密度仪测量了前臂、髋关节和脊柱的骨密度（BMD）。102名年龄和性别匹配的对照人群的骨密度数据可用。在调整年龄和体重指数（BMI）后，1型糖尿病男性患者脊柱骨质减少和骨质疏松症比对照组更常见（P = 0.030）。在1型男性中，在调整年龄和BMI后，BMD、髋关节、股骨颈和脊柱的T-和z -评分均低于年龄匹配的对照组(P
To determine the prevalence and biochemical/hormonal determinants of osteopenia and osteoporosis in adults with Type 1 diabetes.One hundred and two patients (52 female, 50 male) with Type 1 diabetes aged 20-71 years underwent cross-sectional assessment of biochemical/hormonal markers of bone metabolism, and bone mineral density (BMD) measurement at forearm, hip and spine using dual energy x-ray absorptiometry. BMD data were available for 102 age- and gender-matched population-based control subjects.After adjusting for age and body mass index (BMI), osteopenia and osteoporosis were more common at the spine in males with Type 1 diabetes than in control subjects (P = 0.030). In Type 1 males, after adjustment for age and BMI, BMD, T- and Z-scores at the hip, femoral neck and spine were lower compared with age-matched control subjects (P