Long lived microbubbles for oxygen delivery
Long lived microbubbles for oxygen delivery
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DOI：
10.1080/10731190600974939
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发表时间：
2007-01-01
期刊：
影响因子：
--
通讯作者：
Vandamme, Thierry F.
中科院分区：
文献类型：
--
作者：
Gerber, Frederic;Waton, Gilles;Vandamme, Thierry F.
通过使用氟化磷脂代替标准磷脂作为壳成分，获得了含有碳氟化合物作为其填充气体一部分的超长寿命微泡。已经发现碳氟化合物气体和氟化磷脂之间具有出乎意料的强协同效应。这种气泡可用于体内氧气输送、超声对比成像和药物输送。
Exceptionally long lived microbubbles containing a fluorocarbon as part of their filling gas have been obtained by using a fluorinated phospholipid instead of a standard phospholipid as shell component. An unexpected, strong synergistic effect between the fluorocarbon gas and the fluorinated phospholipid has been discovered. Such bubbles could be used for in vivo oxygen delivery, ultrasound contrast imaging and drug delivery.