EPIDEMIOLOGIC STUDIES OF VENEZUELAN EQUINE ENCEPHALITIS VIRUS IN ALMIRANTE PANAMA
EPIDEMIOLOGIC STUDIES OF VENEZUELAN EQUINE ENCEPHALITIS VIRUS IN ALMIRANTE PANAMA
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DOI：
10.1093/oxfordjournals.aje.a120870
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发表时间：
1968-01-01
影响因子：
5
通讯作者：
GALINDO, P
中科院分区：
文献类型：
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作者：
GRAYSON, MA;GALINDO, P
从1961年和1962年在巴拿马热带雨林地区采集或暴露的标本中分离出43株委内瑞拉马脑炎（VEE）病毒。从发热患者中分离出6株，从野外啮齿动物中分离出7株，从至少6种野生鸟类中分离出9株。从至少4种蚊子中获得了12株VEE病毒，9窝暴露于吸血昆虫叮咬的哨兵小鼠也产生了病毒。获得了1961年以前该地区VEE病毒活动的血清学证据。在包括人、马、牛、犬和家禽在内的25种脊椎动物以及几种野生哺乳动物、鸟类和爬行动物中检测到VEE病毒抗体。人类感染VEE病毒的情况很普遍，男女几乎一致，并且与在阿尔米兰特居住的时间和地点有关。VEE可能是巴拿马阿尔米兰特的地方病;啮齿动物，尤其是棉鼠（Sigmodon hispidus），是重要的宿主;库蚊（Melanoconlon）蚊趾，特别是库蚊（C.（M.）taeniopus是该地区最有效的病毒载体。
Forty-three isolations of Venezuelan equine encephalitis (VEE) virus were made from specimens collected or exposed in a tropical rainforest area of Panama during 1961 and 1962. Six isolates were recovered from febrile patients, 7 from field rodents and 9 from at least 6 species of wild birds. Twelve strains of VEE virus were obtained from at least 4 species of mosquitoes, and 9 litters of sentinel mice exposed to the bites of bloodsucking insects also yielded the virus. Serologic evidence of VEE virus activity in the area before 1961 was acquired. Antibodies to VEE virus were detected in 25 species of vertebrates including humans, equines, bovines, canines and domestic fowl as well as several species of wild mammals, birds and reptiles. Human infections with VEE virus were widespread, occurred nearly uniformly in both sexes and were associated with length and place of residence in Almirante. VEE is probably endemic in Almirante, Panama; rodents, especially the cotton rat (Sigmodon hispidus), are important reservoirs; and Culex (Melanoconlon) mosqui-toes, in particular, C. (M.) taeniopus, are the most efficient vectors of this virus in the area.