Randomised controlled trial of effect of high-impact exercise on selected risk factors for osteoporotic fractures
Randomised controlled trial of effect of high-impact exercise on selected risk factors for osteoporotic fractures
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DOI：
10.1016/s0140-6736(96)04214-6
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发表时间：
1996-11-16
期刊：
影响因子：
168.9
通讯作者：
Vuori, I
中科院分区：
文献类型：
--
作者：
Heinonen, A;Kannus, P;Vuori, I
骨质疏松性骨折在老年人中很常见，如果不采取预防措施，这些骨折对卫生保健系统的负担将进一步增加。本随机对照研究的目的是评估，在绝经前妇女，高冲击负荷的影响，对几个决定因素的aperotic fractions.Methods 98名健康，久坐不动的女性志愿者年龄在35-45岁，随机分配到任何一个培训（n=49）或对照组（n=49）。每周进行三次渐进式高冲击力练习，持续18个月。我们在基线和12个月及18个月后，通过双能X线吸收法测量特定中轴和下肢部位的骨矿物质密度（BMD）。最大等长力量，肌肉和心血管性能，动态balances.Findings股骨颈，负重部位的骨密度增加显着更多的训练组（平均1。6% [95% CI 0 . 8-2 . 4])与对照组相比（0 . 6% [-0 .二比一4]，p=0。006）。相比之下，在非负重部位，如桡骨远端，训练组和对照组之间没有显著差异（-1。5% [-2。七比零3]vs-0. 7% [-1。九比零5]，p=0。60）。在训练组有一个显着的改善，在垂直跳跃和最大的运动与controls.Interpretation预测每分钟的耗氧量高冲击运动，负荷骨与快速上升的力量配置文件中的多才多艺的运动提高完整性，肌肉性能，和动态的绝经前妇女。如果定期进行，这种类型的运动可能有助于降低晚年发生骨质疏松性骨折的风险。需要长期研究来证明这些18个月的结果是否可以转化为长期益处。
Background Osteoporotic fractures among the elderly are common, and without preventive measures the burden of these fractures on health-care systems will increase further. The purpose of this randomised controlled study was to evaluate, in premenopausal women, the effects of high-impact loading on several determinants of osteoporotic fractures.Methods 98 healthy, sedentary female volunteers aged 35-45 years were randomly assigned to either a training (n=49) or a control group (n=49). Progressive high-impact exercises were done three times per week for 18 months. We measured bone mineral density (BMD) in specific axial and lower-limb sites, by dual-energy X-ray absorptiometry, at baseline and after 12 and 18 months. Maximum isometric strength, muscular and cardiovascular performance, and dynamic balance were also assessed.Findings BMD at the femoral neck, a weightbearing site, increased significantly more in the training group (mean 1 . 6% [95% CI 0 . 8-2 . 4]) than in the control group (0 . 6% [-0 . 2 to 1 . 4], p=0 . 006). By contrast, at non-weightbearing sites, such as the distal radius, there was no significant difference between the training and control groups (-1 . 5% [-2 . 7 to -0 . 3] vs -0 . 7% [-1 . 9 to -0 . 5], p=0 . 60). In the training group there was a significant improvement in vertical jump and predicted oxygen consumption per min at maximum exercise compared with controls.Interpretation High-impact exercises that load bones with a rapidly rising force profile in versatile movements improve integrity, muscular performance, and dynamic in premenopausal women. If done on a regular basis, this type of exercise may help decrease the risk of osteoporotic fractures in later life. Long-term studies are required to show whether these 18-month results can be translated into long-term benefit.