The Prevalence of Anxiety Disorders During Pregnancy and the Postpartum Period: A Multivariate Bayesian Meta-Analysis
The Prevalence of Anxiety Disorders During Pregnancy and the Postpartum Period: A Multivariate Bayesian Meta-Analysis
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DOI：
10.4088/jcp.18r12527
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发表时间：
2019-07-01
影响因子：
5.3
通讯作者：
Fawcett, Jonathan M.
中科院分区：
文献类型：
--
作者：
Fawcett, Emily J.;Fairbrother, Nichole;Fawcett, Jonathan M.
目的：为了估计焦虑症在孕妇和产后妇女的患病率，并确定预测因素占变异性across estimates.Data Sources：电子搜索PsycINFO和PubMed从开始到2016年7月进行，没有日期或语言限制，并补充所获得的来源中引用的文章。一个布尔搜索短语利用相关的关键字怀孕，产后，患病率和特定的anxiety disorders.Study选择：文章报道的患病率1个或多个8常见的焦虑症在怀孕或产后妇女被列入。共检索到2，613条记录，最终纳入26项研究。数据提取：从每个研究中提取焦虑症患病率和潜在的预测变量（例如，产次）。贝叶斯多变量建模方法估计了每种疾病的患病率和研究间异质性以及患有1种或多种焦虑症的患病率。个体疾病患病率估计值从创伤后应激障碍的1.1%到特定恐惧症的4.8%不等，患有至少一种或多种焦虑症的患病率估计为20.7%（95%最高密度区间[16.7%至25.4%]）。观察到大量的研究间异质性，表明“真实”患病率在样本间差异很大。有证据表明，一个小的（3.1%）的倾向，孕妇更容易患焦虑症比产后women.Conclusions：围产期焦虑症比以前认为的更普遍，在一个典型的样本中有1/5的妇女满足诊断标准，至少有1种疾病。这些发现强调了在妇产科环境中进行焦虑筛查、教育和转诊的必要性。
Objective: To estimate the prevalence of anxiety disorders in pregnant and postpartum women and identify predictors accounting for variability across estimates.Data Sources: An electronic search of PsycINFO and PubMed was conducted from inception until July 2016, without date or language restrictions, and supplemented by articles referenced in the obtained sources. A Boolean search phrase utilized a combination of keywords related to pregnancy, postpartum, prevalence, and specific anxiety disorders.Study Selection: Articles reporting the prevalence of 1 or more of 8 common anxiety disorders in pregnant or postpartum women were included. A total of 2,613 records were retrieved, with 26 studies ultimately included.Data Extraction: Anxiety disorder prevalence and potential predictor variables (eg, parity) were extracted from each study. A Bayesian multivariate modeling approach estimated the prevalence and between-study heterogeneity of each disorder and the prevalence of having 1 or more anxiety disorder.Results: Individual disorder prevalence estimates ranged from 1.1% for posttraumatic stress disorder to 4.8% for specific phobia, with the prevalence of having at least 1 or more anxiety disorder estimated to be 20.7% (95% highest density interval [16.7% to 25.4%]). Substantial between-study heterogeneity was observed, suggesting that "true" prevalence varies broadly across samples. There was evidence of a small (3.1%) tendency for pregnant women to be more susceptible to anxiety disorders than postpartum women.Conclusions: Peripartum anxiety disorders are more prevalent than previously thought, with 1 in 5 women in a typical sample meeting diagnostic criteria for at least 1 disorder. These findings highlight the need for anxiety screening, education, and referral in obstetrics and gynecology settings.