Anastomotic leakage after colorectal cancer surgery: a risk factor for recurrence and poor prognosis.
Anastomotic leakage after colorectal cancer surgery: a risk factor for recurrence and poor prognosis.
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结直肠癌术后吻合口瘘：复发和预后不良的危险因素。
DOI：
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发表时间：
1993
影响因子：
2.4
通讯作者：
Masaki Kitajima
中科院分区：
文献类型：
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作者：
Shin Fujita;T. Teramoto;Masahiko Watanabe;Susumu Kodaira;Masaki Kitajima
为探讨结直肠癌术后吻合口瘘的复发率及预后，对庆应义塾大学医院1970~1990年间980例结直肠癌吻合口瘘患者进行了检查。980例患者中有33例（泄漏组）出现吻合口泄漏。渗漏组局部复发率明显高于无渗漏组（P <0.01）。Dukes 'A、B期患者渗漏组无瘤生存率明显低于无渗漏组（P <0.01），而Dukes' C、D期患者无瘤生存率无明显差异。提示结直肠癌术后吻合口瘘可增加局部复发率，使预后不良。
In order to discover the incidence of recurrence and prognosis of patients with anastomotic leakage after colorectal surgery, 980 colorectal cancer patients who underwent anastomosis at Keio University Hospital between 1970 and 1990 were examined. Thirty-three patients (leakage group) out of the 980 exhibited anastomotic leakage. The incidence of local recurrence in the leakage group was significantly higher than in the no leakage group (P < 0.01). The disease-free survival rate of the leakage group was significantly lower than that of the no leakage group in Dukes' A, B patients (P < 0.01), but was not so in Dukes' C, D patients. These results suggested that anastomotic leakage after colorectal cancer surgery might enhance the incidence of local recurrence and make the prognosis poor.