The Striatum: Where Skills and Habits Meet

The Striatum: Where Skills and Habits Meet
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DOI:
10.1101/cshperspect.a021691
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发表时间:
2015-08-01
影响因子:
7.2
通讯作者:
Grafton, Scott T.
Grafton, Scott T.
中科院分区:
生物学1区
文献类型:
--
作者:
Graybiel, Ann M.;Grafton, Scott T.

文献摘要

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经过世纪对基底神经节运动功能的研究,新的观点出现了,这表明基底神经节也具有与学习习惯和获得运动技能有关的主要功能。我们回顾的证据支持纹状体的作用,优化行为,通过完善行动的选择,并在形成习惯和技能作为一个调制器的运动剧目。这些发现挑战了纹状体学习过程仅限于运动域的概念。由纹状体回路支持的学习机制可以推广到其他领域,包括认知技能和与情感相关的行为模式。
After more than a century of work concentrating on the motor functions of the basal ganglia, new ideas have emerged, suggesting that the basal ganglia also have major functions in relation to learning habits and acquiring motor skills. We review the evidence supporting the role of the striatum in optimizing behavior by refining action selection and in shaping habits and skills as a modulator of motor repertoires. These findings challenge the notion that striatal learning processes are limited to the motor domain. The learning mechanisms supported by striatal circuitry generalize to other domains, including cognitive skills and emotion-related patterns of action.