Prospective study of human herpesvirus 6, human herpesvirus 7, and cytomegalovirus infections in human immunodeficiency virus-positive patients.
Prospective study of human herpesvirus 6, human herpesvirus 7, and cytomegalovirus infections in human immunodeficiency virus-positive patients.
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人类免疫缺陷病毒阳性患者中人类疱疹病毒 6 型、人类疱疹病毒 7 型和巨细胞病毒感染的前瞻性研究。
DOI：
10.1128/jcm.35.10.2657-2659.1997
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发表时间：
1997
影响因子：
9.4
通讯作者：
Clark,DA
中科院分区：
文献类型：
--
作者：
Fabio,G;Knight,SN;Kidd,IM;Noibi,SM;Johnson,MA;Emery,VC;Griffiths,PD;Clark,DA
通过PCR监测人类免疫缺陷病毒（HIV）阳性患者的血液样本中的巨细胞病毒（CMV）、人类疱疹病毒6型（HHV-6）和HHV-7。我们在17%的患者中检测到CMV，6%检测到HHV-6，3%检测到HHV-7。CMV病毒载量显著高于HHV-6（P = 0.007）和HHV-7（P = 0.01）。CMV和HHV-6的检测分别与低和高CD 4计数相关。
Blood samples from human immunodeficiency virus (HIV)-positive patients were monitored for cytomegalovirus (CMV), human herpesvirus 6 (HHV-6), and HHV-7 by PCR. We detected CMV in 17% of the patients, HHV-6 in 6%, and HHV-7 in 3%. The viral loads of CMV were significantly higher than those of HHV-6 (P = 0.007) or HHV-7 (P = 0.01). Detection of CMV and HHV-6 was associated with low and high CD4 counts, respectively.