Chiral Scandium-Catalyzed Enantioselective Hydroxymethylation of Ketones in Water
Chiral Scandium-Catalyzed Enantioselective Hydroxymethylation of Ketones in Water
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DOI：
10.1002/asia.200900442
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发表时间：
2010-01-01
影响因子：
4.1
通讯作者：
Nagano, Takashi
中科院分区：
文献类型：
--
作者：
Kobayashi, Shu;Kokubo, Masaya;Nagano, Takashi
Scandium-catalyzed enantioselective hydroxymethylation of ketones has been developed using aqueous formaldehyde (formalin) in water. The addition of a catalytic amount of pyridine enables the use of ketones directly in asymmetric hydroxymethylation reactions.(Chemical equation presented).
