The effect of cataract surgery on neuropsychological test performance: A randomized controlled trial
The effect of cataract surgery on neuropsychological test performance: A randomized controlled trial
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DOI：
10.1017/s1355617706060954
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发表时间：
2006-09-01
影响因子：
2.6
通讯作者：
Von Sanden, Chwee
中科院分区：
文献类型：
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作者：
Anstey, Kaarin J.;Lord, Stephen R.;Von Sanden, Chwee
最近的横断面研究报告了视觉和认知功能之间的强关联，纵向研究表明晚年视觉和认知能力下降之间的关系。据报道，轻度认知障碍患者在白内障手术后认知能力有所改善。我们调查了白内障手术改善视功能是否会改善健康老年人的神经心理学表现。对56例双侧白内障患者（平均年龄73岁）进行了一项在急性医院进行的白内障手术的随机临床试验，在筛选阶段排除了54例患者，其中53例不符合视力标准，1例没有白内障。家庭评估包括视觉和神经心理功能，计算机认知测试和健康问卷。结果表明，认知正常的成年人白内障手术没有认知方面的好处。我们的结论是，白内障手术后的视力改善与其他健康成年人的神经心理测试表现的改善没有强烈的相关性。晚年视觉和认知功能之间的联合关联可能是由于中心因素，而不太可能与眼部疾病密切相关。视觉功能改善所带来的短期神经刺激增加似乎不会影响认知能力。
Recent cross-sectional studies have reported strong associations between visual and cognitive function, and longitudinal studies have shown relationships between visual and cognitive decline in late life. Improvement in cognitive performance after cataract surgery has been reported in patients with Mild Cognitive Impairment. We investigated whether improving visual function with cataract surgery would improve neuropsychological performance in healthy older adults. A randomized clinical trial of cataract surgery performed at acute hospitals was conducted on 56 patients (mean age 73) with bilateral cataract, after excluding a total of 54 patients at the screening stage, of whom 53 did not meet visual acuity criteria and one did not have cataract. In-home assessments included visual and neuropsychological function, computerized cognitive testing and health questionnaires. Results showed no cognitive benefits of cataract surgery in cognitively normal adults. We conclude that visual improvement following cataract surgery is not strongly associated with an improvement in neuropsychological test performance in otherwise healthy adults. Joint associations between visual and cognitive function in late life are likely to be due to central factors, and unlikely to be strongly related to eye disease. Short-term increased neural stimulation from improved visual function does not appear to affect cognitive performance.