SOLVENT-INDUCED FORCES IN PROTEIN FOLDING

SOLVENT-INDUCED FORCES IN PROTEIN FOLDING
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DOI:
10.1021/j100380a065
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发表时间:
1990-08-23
影响因子:
--
通讯作者:
BENNAIM, A
BENNAIM, A
中科院分区:
其他
文献类型:
--
作者:
BENNAIM, A

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研究了蛋白质上不同基团之间的溶剂诱导力。发现分子内亲水力可能是通过溶剂介导的最强力。有人认为,这些可能是最重要的溶剂诱导的蛋白质折叠过程中的驱动力。
The solvent-induced forces between various groups on the protein are examined. It is found that the intramolecular hydrophilic forces are likely to be the strongest forces mediated through the solvent. It is argued that these are probably the most important solvent-induced driving forces in the process of protein folding.