Rec-mediated recombinational hot spot activity in bacteriophage λ
Rec-mediated recombinational hot spot activity in bacteriophage λ
复制标题
Rec介导的噬菌体重组热点活性λ
DOI:
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发表时间:
1974
期刊:
影响因子:
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通讯作者:
M. Stahl
中科院分区:
文献类型:
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作者:
F. Stahl;M. Stahl
SummaryA Chi mutation in phage λ stimulates Rec-mediated crossing over more to one side of itself than to the other; stimulation, which is maximal near Chi, can occur at some distance from the Chi site as well. A gross heterology differentiating the two recombining parents does not interfere with the distant Chi-stimulated crossover whether the heterology is at the Chi site or between the Chi site and the distant interval in which recombination is monitored. These conclusions hold whether recombination is measured “genetically” in standard crosses or “physically” in density-labeled crosses conducted in the absence of DNA replication.