HERPESVIRUS-SIMIAE CONTAMINATION OF PRIMARY RHESUS-MONKEY KIDNEY-CELL CULTURES - CDC RECOMMENDATIONS TO MINIMIZE RISKS TO LABORATORY PERSONNEL
HERPESVIRUS-SIMIAE CONTAMINATION OF PRIMARY RHESUS-MONKEY KIDNEY-CELL CULTURES - CDC RECOMMENDATIONS TO MINIMIZE RISKS TO LABORATORY PERSONNEL
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DOI：
10.1016/0732-8893(89)90099-0
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发表时间：
1989-07-01
影响因子：
2.9
通讯作者：
SCHONBERGER, LB
中科院分区：
文献类型：
--
作者：
WELLS, DL;LIPPER, SL;SCHONBERGER, LB
猴疱疹病毒（Herpesvirussimiae）或B病毒是在恒河猴（Macacamulatta）、食蟹猴（Cynomolgus）（M. fascicularis）和其他猕猴属的亚洲猴。这种病毒存在于这些猴子的血液、分泌物和组织中。B病毒对人类具有致病性，可引起危及生命的中枢神经系统感染。本通讯描述了原代恒河猴肾（pMK）培养细胞中B病毒污染的发现，并提供了pMK培养细胞的处理指南。
Herpesvirus simiae, or B virus, is a member of the herpes group of viruses that are enzootic in rhesus (Macaca mulatta), cynomolgus (M. fascicularis), and other Asiatic monkeys of the genus Macaca. The virus is found in the blood, secretions, and tissues of these monkeys. B virus is pathogenic in humans and can cause life-threatening central nervous system infections. This communication describes the finding of B virus contamination of primary rhesus monkey kidney (pMK) culture cells, and provides guidelines for the handling of pMK culture cells.