Gait adaptations with aging in healthy participants and people with knee joint osteoarthritis
Gait adaptations with aging in healthy participants and people with knee joint osteoarthritis
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DOI：
10.1016/j.gaitpost.2017.06.015
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发表时间：
2017-09-01
期刊：
影响因子：
2.4
通讯作者：
McGregor, Alison H.
中科院分区：
文献类型：
--
作者：
Duffell, Lynsey D.;Jordan, Stevan J.;McGregor, Alison H.
内侧间室骨关节炎（OA）患者和非OA患者的年龄和步态特征之间的关系尚不清楚。我们的目的是描述这种关系，并在一个子集的OA患者的生物力学和结构参数。招募了25名诊断为单侧内侧膝关节OA的参与者和84名健康参与者，没有已知的膝关节病理学。3D运动捕捉用于分析矢状面和冠状面步态参数，同时参与者以舒适的速度行走。根据年龄（18-30岁，31-59岁和60岁以上）对参与者进行分类，并在年龄组之间和年龄组内对患有和不患有OA的参与者进行比较。在OA患者的一个子集中，使用临床可用的计算机断层扫描图像来评估关节结构。在髋关节和膝关节的冠状面运动学的差异，特别是那些与我们的健康对照组相比，年龄较大的OA参与者，以及增加膝关节力矩。膝关节内收力矩与OA患者亚组的结构参数相关。在仅患有OA的老年参与者中观察到膝关节力矩增加和运动学改变，这似乎与OA引起的关节形态学变化相关，而不是与内侧膝关节OA的初始原因相关。
The relationship between age and gait characteristics in people with and without medial compartment os-teoarthritis (OA) remains unclear. We aimed to characterize this relationship and to relate biomechanical and structural parameters in a subset of OA patients. Twenty five participants with diagnosed unilateral medial knee OA and 84 healthy participants, with no known knee pathology were recruited. 3D motion capture was used to analyse sagittal and coronal plane gait parameters while participants walked at a comfortable speed. Participants were categorized according to age (18-30, 31-59 and 60 + years), and those with and without OA were compared between and within age groups. In a subset of OA patients, clinically available Computed Tomography images were used to assess joint structure. Differences in coronal plane kinematics at the hip and knee were noted in participants with OA particularly those who were older compared with our healthy controls, as well as increased knee moments. Knee adduction moment correlated with structural parameters in the subset of OA patients. Increased knee moments and altered kinematics were observed in older participants presenting with OA only, which seem to be related to morphological changes in the joint due to OA, as opposed to being related to the initial cause of medial knee OA.